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class Gtk3::Spec::FixedSizes::GdkWindow Association of angiotensin-converting enzyme gene polymorphism (I/D) with microalbuminuria and normal albumin excretion in nondiabetic Chinese.
The insertion-deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene has been shown to be associated with the severity of diabetic nephropathy in Caucasians and with microalbuminuria in African-Americans, but its association with normal albumin excretion in diabetic patients is unclear. The aim of this study was to explore whether there is an association between this polymorphism and microalbuminuria in nondiabetic Chinese. ACE genotypes were assessed in 127 nondiabetic Chinese hypertensive patients with normal albumin excretion, 60 nondiabetic Chinese hypertensive patients with persistent microalbuminuria, and 76 nondiabetic Chinese normal subjects. The ACE genotype frequency was different in these three groups (chi(2) = 11.082, P =.0012). The distribution of I/I, I/D, and D/D genotypes in the patients with microalbuminuria was significantly different from that in the patients
https://colab.research.google.com/drive/1hRKtPP5ZgvTPQ19L4klk8h6_uZBib9mt
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